gamma-Aminobutyric acid


GABA Molecule : GABA (gamma-aminobutyric acid) helps to modulate the action of dopamine, norepinephrine, and serotonin. Unlike the other neurotransmitters, it occurs almost exclusively in the CNS and is present in a large percentage of neurons of the brain. Several studies have suggested that some individuals with depression have reduced production of GABA, and that it may play a role in the patient's experience of depression and other mental disorders. GABA is considered a primary neurotransmitter because its effects are very specific.

gamma-Aminobutyric acid (γ-Aminobutyric acid) /ˈɡæmə əˈmnbjuːˈtɪrk ˈæsd/ (also called GABA /ˈɡæbə/ for short) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone.

Although in chemical terms it is an amino acid (as it has both a primary amine and a carboxylic acid functional group), GABA is rarely referred to as such in the scientific or medical communities. By convention the term "amino acid", when used without a qualifier, refers specifically to an alpha amino acid. GABA is not an alpha amino acid, nor is it considered to be incorporated into proteins.


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