17-Hydroxyprogesterone

17-Hydroxyprogesterone

Other names: 17-OHP, 17-OH Progesterone, Progesterone 17-OH
Specimen: Blood

ng/dL

 
1
200

Your 17-Hydroxyprogesterone is

Normal blood level of 17-OHP for an infant is less than 100 ng/dL (nanograms per deciliter). For adults, normal blood level of 17-OHP is less than 200 ng/dL. Women's normal levels vary depending on the phase of their menstrual cycle when the blood sample is taken.

17-OHP is a hormone produced by the adrenal glands and the sex organs. 17-OHP is used by the body to make cortisol. Cortisol, a hormone produced by the adrenal glands, helps break down protein, glucose, and lipids, maintain blood pressure, and regulate the immune system. Its levels vary throughout the day, and rise in response to stress. If an enzyme deficiency causes the body to produce too little cortisol, its precursors -- including 17-OHP -- can accumulate in the blood. This can prompt the adrenal glands to create more androgens, or male sex hormones, to mop up the 17-OHP.
High levels of OHP often indicate a disorder called congenital adrenal hyperplasia (CAH), an inherited disorder that affects the adrenal gland. If an infant is born with outer genitalia that is not clearly male or female, the test is usually performed. This test can also help diagnose nonclassical adrenal hyperplasia, a milder form of the disorder. This condition occurs when the body does not make enough of a substance that helps the adrenal gland make cortisol. It can interfere with growth, development, and fertility.
Some newborns are routinely screened for 17-OHP. When an infant is born with ambiguous genitalia, the test is usually performed. The test may be indicated for a young woman develops hair in a growth pattern typical of males or has other symptoms associated with high androgen levels, such as a low voice or increase in muscle mass. Boys who exhibit premature sexual development may also be tested.
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