Low-Density Lipoprotein


Image Caption : Low-Density Lipoprotein molecule : A lipoprotein (from the Greek lipos, for fat) is a fat-and-protein package that enables fats and cholesterol to move freely within the bloodstream (fats and blood, like oil and water, do not mix). Proteins and other components make up the outer shell of the lipoprotein; cholesterol and other fats are packed together inside. The size and density of the lipoprotein determines whether its cholesterol is classified as "good" or "bad." Low-density lipoproteins (LDL) are larger, lighter, and fluffier; high-density lipoproteins (HDL) are small and dense. LDL cholesterol, HDL cholesterol and other lipid components contribute to your total blood cholesterol value.

Lipoproteins, LDL

A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.

National Center for Biotechnology Information, U.S. National Library of Medicine

Low-density lipoprotein (LDL) (lip-o-PRO-teen) LDL is a compound made up of fat and protein that carries cholesterol in the blood from the liver to other parts of the body. High levels of LDL cholesterol, commonly called "bad" cholesterol, cause a buildup of cholesterol in the arteries and increase the risk of heart disease. An LDL level of less than 100 mg/dL is considered optimal, 100 to 129 mg/dL is considered near or above optimal, 130 to 159 mg/dL is considered borderline high, 160 to 189 mg/dL is considered high, and 190 mg/dL or greater is considered very high.



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