Vitamin K Molecule


Image Caption : Vitamin K is a fat-soluble vitamin that plays a critical role in the function of several proteins involved in normal blood clotting. It also assists in the promotion of bone health. There are two natural forms of Vitamin K: Vitamin K1 and Vitamin K2. Vitamin K1, or phylloquinone, is synthesized by plants. Vitamin K2, or menoquinone, is created by bacteria in the small intestines. The three synthetic forms of Vitamin K are K3, K4, and K5.

It`s rare to have a Vitamin K deficiency since bacteria in the intestines can make the vitamin. However, since intestinal bacteria populations are low at birth, newborns are commonly administered a Vitamin K injection. Food sources rich in the vitamin include beef liver, green tea, turnip greens, broccoli, kale, spinach, cabbage, asparagus, and dark green lettuce.

In this model, carbon atoms are dark gray, hydrogen atoms are white, and oxygen atoms are red.

Vitamin K

Vitamin K helps your body by making proteins for healthy bones and tissues. It also makes proteins for blood clotting. If you don't have enough vitamin K, you may bleed too much.

Newborns have very little vitamin K. They usually get a shot of vitamin K soon after they are born.

If you take blood thinners, you need to be careful about how much vitamin K you get. You also need to be careful about taking vitamin E supplements. Vitamin E can interfere with how vitamin K works in your body. Ask your health care provider for recommendations about these vitamins.

There are different types of vitamin K. Most people get vitamin K from plants such as green vegetables, and dark berries. Bacteria in your intestines also produce small amounts of another type of vitamin K.

Vitamin K

Fact Sheet for Consumers

What is vitamin K and what does it do?

Vitamin K is a nutrient that the body needs to stay healthy. It's important for blood clotting and healthy bones and also has other functions in the body. If you are taking a blood thinner such as warfarin (Coumadin®), it's very important to get about the same amount of vitamin K each day.

How much vitamin K do I need?

The amount of vitamin K you need depends on your age and sex. Average daily recommended amounts are listed below in micrograms (mcg).

Life StageRecommended Amount
Birth to 6 months 2.0 mcg
7–12 months 2.5 mcg
1–3 years 30 mcg
4–8 years 55 mcg
9–13 years 60 mcg
14–18 years 75 mcg
Adult men 19 years and older 120 mcg
Adult women 19 years and older 90 mcg
Pregnant or breastfeeding teens 75 mcg
Pregnant or breastfeeding women 90 mcg

What foods provide vitamin K?

Vitamin K is found naturally in many foods. You can get recommended amounts of vitamin K by eating a variety of foods, including the following:

  • Green leafy vegetables, such as spinach, kale, broccoli, and lettuce
  • Vegetable oils
  • Some fruits, such as blueberries and figs
  • Meat, cheese, eggs, and soybeans

You can find links to more food sources of vitamin K in the last section of this fact sheet, Where can I find out more about Vitamin K?

What kinds of vitamin K dietary supplements are available?

Vitamin K is found in multivitamin/multimineral supplements. Vitamin K is also available in supplements of vitamin K alone or of vitamin K with a few other nutrients such as calcium, magnesium, and/or vitamin D. Common forms of vitamin K in dietary supplements are phylloquinone and phytonadione (also called vitamin K1), menaquinone-4, and menaquinone-7 (also called vitamin K2).

Am I getting enough vitamin K?

Vitamin K deficiency is very rare. Most people in the United States get enough vitamin K from the foods they eat. Also, bacteria in the colon make some vitamin K that the body can absorb. However, certain groups of people may have trouble getting enough vitamin K:

  • Newborns who don't receive an injection of vitamin K at birth
  • People with conditions (such as cystic fibrosis, celiac disease, ulcerative colitis, and short bowel syndrome) that decrease the amount of vitamin K their body absorbs
  • People who have had bariatric (weight loss) surgery

What happens if I don't get enough vitamin K?

Severe vitamin K deficiency can cause bruising and bleeding problems because the blood will take longer to clot. Vitamin K deficiency might reduce bone strength and increase the risk of getting osteoporosis because the body needs vitamin K for healthy bones.

What are some effects of vitamin K on health?

Scientists are studying vitamin K to understand how it affects our health. Here are some examples of what this research has shown.

Osteoporosis
Vitamin K is important for healthy bones. Some research shows that people who eat more vitamin K-rich foods have stronger bones and are less likely to break a hip than those who eat less of these foods. A few studies have found that taking vitamin K supplements improves bone strength and the chances of breaking a bone, but other studies have not. More research is needed to better understand if vitamin K supplements can help improve bone health and reduce osteoporosis risk.

Coronary heart disease
Scientists are studying whether low blood levels of vitamin K increase the risk of heart disease, perhaps by making blood vessels that feed the heart stiffer and narrower. More research is needed to understand whether vitamin K supplements might help prevent heart disease.

Can vitamin K be harmful?

Vitamin K has not been shown to cause any harm. However, it can interact with some medications, particularly warfarin (Coumadin®)-see the information below.

Are there any interactions with vitamin K that I should know about?

Yes, some medications may interact with vitamin K. Here are a few examples:

Warfarin (Coumadin®)
Vitamin K can have a serious interaction with the blood thinner warfarin (Coumadin®). If you take warfarin, make sure that the amount of vitamin K you consume from food and supplements is about the same every day. A sudden change in the amount of vitamin K you get can cause dangerous bleeding (if you consume less) or blood clots (if you consume more). You can find more information on the interaction between vitamin K and Coumadin® in this publicationexternal link disclaimer from the National Institutes of Health.

Antibiotics
Antibiotics can destroy the good bacteria in your gut. Some of these bacteria make vitamin K. Using antibiotics for more than a few weeks may reduce the amount of vitamin K made in your gut and therefore, the amount available for your body to use.

Bile acid sequestrants
Some people take bile acid sequestrants (such as cholestyramine [Questran®] and colestipol [Colestid®]) to lower blood cholesterol levels. These medications can reduce the amount of vitamin K your body absorbs, especially if you take them for many years.

Orlistat
Orlistat (Alli® and Xenical®) is a weight-loss drug. It reduces the amount of fat your body absorbs and can decrease the absorption of vitamin K.

Tell your doctor, pharmacist, and other health care providers about any dietary supplements and prescription or over-the-counter medicines you take. They can tell you if the dietary supplements might interact with your medicines or if the medicines might interfere with how your body absorbs, uses, or breaks down nutrients such as vitamin K.

Vitamin K and healthful eating

People should get most of their nutrients from food, advises the federal government's Dietary Guidelines for Americans. Foods contain vitamins, minerals, dietary fiber and other substances that benefit health. Dietary supplements might help in some situations to increase the intake of a specific vitamin or mineral. For more information on building a healthy diet, refer to the Dietary Guidelines for Americans external link disclaimer and the U.S. Department of Agriculture's ChooseMyPlate external link disclaimer.

Disclaimer

This fact sheet by the Office of Dietary Supplements provides information that should not take the place of medical advice. We encourage you to talk to your healthcare providers (doctor, registered dietitian, pharmacist, etc.) about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Any mention in this publication of a specific brand name is not an endorsement of the product.

NIH Office of Dietary Supplements



The material on this site is for informational purposes only and is not intended as medical advice. It should not be used to diagnose or treat any medical condition. Consult a licensed medical professional for the diagnosis and treatment of all medical conditions and before starting a new diet or exercise program. If you have a medical emergency, call 911 immediately.