Vitamin B2 (Riboflavin) Molecule


Image Caption : Riboflavin, also known as Vitamin B2, is a water-soluble nutrient (like all B vitamins). Molecules of riboflavin are active in the body as coenzymes, meaning that they attach to an enzyme and are essential for its function. Coenzymes derived from riboflavin are termed flavocoenzymes, and enzymes that use a flavocoenzyme are called flavoproteins.

Most plant- and animal-derived foods contain at least small quantities of riboflavin. Because so many foods contain riboflavin - and because those that don`t are often fortified - riboflavin deficiency is rare in the U.S.

In this model, carbon atoms are dark gray, hydrogen atoms are white, nitrogen atoms are blue, and oxygen atoms are red.

B Vitamins

The B vitamins are

  • B1 (thiamine)
  • B2 (riboflavin)
  • B3 (niacin)
  • B5 (pantothenic acid)
  • B6
  • B7 (biotin)
  • B12
  • Folic acid

These vitamins help the process your body uses to get or make energy from the food you eat. They also help form red blood cells. You can get B vitamins from proteins such as fish, poultry, meat, eggs, and dairy products. Leafy green vegetables, beans, and peas also have B vitamins. Many cereals and some breads have added B vitamins.

Not getting enough of certain B vitamins can cause diseases. A lack of B12 or B6 can cause anemia.

Riboflavin

Fact Sheet for Consumers

This is a reader-friendly overview of riboflavin. For more details, see our health professional fact sheet on riboflavin.

What is riboflavin and what does it do?

Riboflavin (also called vitamin B2) is important for the growth, development, and function of the cells in your body. It also helps turn the food you eat into the energy you need.

How much riboflavin do I need?

The amount of riboflavin you need depends on your age and sex. Average daily recommended amounts are listed below in milligrams (mg).

Life StageRecommended Amount
Birth to 6 months 0.3 mg
Infants 7–12 months 0.4 mg
Children 1–3 years 0.5 mg
Children 4–8 years 0.6 mg
Children 9–13 years 0.9 mg
Teen boys 14–18 years 1.3 mg
Teen girls 14–18 years 1.0 mg
Men 1.3 mg
Women 1.1 mg
Pregnant teens and women 1.4 mg
Breastfeeding teens and women 1.6 mg

What foods provide riboflavin?

Riboflavin is found naturally in some foods and is added to many fortified foods. You can get recommended amounts of riboflavin by eating a variety of foods, including the following:

  • Eggs, organ meats (such as kidneys and liver), lean meats, and low-fat milk
  • Green vegetables (such as asparagus, broccoli, and spinach)
  • Fortified cereals, bread, and grain products

What kinds of riboflavin dietary supplements are available?

Riboflavin is found in multivitamin/multimineral supplements, in B-complex dietary supplements, and in supplements containing only riboflavin. Some supplements have much more than the recommended amounts of riboflavin, but your body can't absorb more than about 27 mg at a time.

Am I getting enough riboflavin?

Most people in the United States get enough riboflavin from the foods they eat and deficiencies are very rare. However, certain groups of people are more likely than others to have trouble getting enough riboflavin:

  • Athletes who are vegetarians (especially strict vegetarians who avoid dairy foods and eggs)
  • Pregnant women and breastfeeding women and their babies
  • People who are vegan
  • People who do not eat dairy foods
  • People with a genetic disorder that causes riboflavin deficiency (such as infantile Brown-Vialetto-Van Laere syndrome)

What happens if I don't get enough riboflavin?

You can develop riboflavin deficiency if you don't get enough riboflavin in the foods you eat, or if you have certain diseases or hormone disorders.

Riboflavin deficiency can cause skin disorders, sores at the corners of your mouth, swollen and cracked lips, hair loss, sore throat, liver disorders, and problems with your reproductive and nervous systems.

Severe, long-term riboflavin deficiency causes a shortage of red blood cells (anemia), which makes you feel weak and tired. It also causes clouding of the lens in your eyes (cataracts), which affects your vision.

What is an effect of riboflavin supplements on health?

Scientists are studying riboflavin to better understand how it affects health. Here is an example of what this research has shown.

Migraine headache

Some studies show that riboflavin supplements might help prevent migraine headaches, but other studies do not. Riboflavin supplements usually have very few side effects, so some medical experts recommend trying riboflavin, under the guidance of a health care provider, for preventing migraines.

Can riboflavin be harmful?

Riboflavin has not been shown to cause any harm.

Are there any interactions with riboflavin that I should know about?

Riboflavin is not known to interact with any medications. But it's always important to tell your doctor, pharmacist, and other health care providers about any dietary supplements and prescription or over-the-counter medicines you take. They can tell you if the dietary supplements might interact with your medicines or if the medicines might interfere with how your body absorbs, uses, or breaks down nutrients.

Riboflavin and healthful eating

People should get most of their nutrients from food, advises the federal government's Dietary Guidelines for Americans. Foods contain vitamins, minerals, dietary fiber and other substances that benefit health. Dietary supplements might help in some situations to increase the intake of a specific vitamin or mineral. For more information on building a healthy diet, refer to the Dietary Guidelines for Americansexternal link disclaimer and the U.S. Department of Agriculture's ChooseMyPlateexternal link disclaimer.

Disclaimer

This fact sheet by the Office of Dietary Supplements provides information that should not take the place of medical advice. We encourage you to talk to your healthcare providers (doctor, registered dietitian, pharmacist, etc.) about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Any mention in this publication of a specific brand name is not an endorsement of the product.

NIH Office of Dietary Supplements



The material on this site is for informational purposes only and is not intended as medical advice. It should not be used to diagnose or treat any medical condition. Consult a licensed medical professional for the diagnosis and treatment of all medical conditions and before starting a new diet or exercise program. If you have a medical emergency, call 911 immediately.